The Psychology of Placebo: Science Explained

A deep dive into the psychological science behind Placebo — what research says.

A placebo is a substance or medical procedure that resembles an actual treatment but does not actually act on a disease or medical condition; in effect it is a fake treatment, offered for experimental or other reasons. For some people, however, placebos can still have a positive or negative effect on symptoms, if only for a brief period of time.

The Benefits and Limitations of Placebos

While the effects are generally temporary, placebo treatments play a role in understanding the brain-mind-body connection in both medical practice and biomedical research. Placebos are often used in medical research to help determine if the effects of a new treatment are actually due to the treatment itself, rather than some other factor.

In a double-blind study, for instance, volunteers don’t know if they are getting the actual treatment or a placebo, so the results can be considered unbiased. Ethical guidelines have been established to prevent the misuse of placebo treatments.

Several factors influence how well a placebo works , including the individual’s expectancy, their motivation to improve their health, external conditioning (e.g., advertising ), and the brain’s ability to produce pain-relieving chemicals called endogenous opiates.

A placebo may involve a “fake” treatment (e.g., placebo pills, saline injections, sham surgeries, etc.), but if it works, real physiological changes take place in the body.

Explore More About Placebo

For a comprehensive understanding of placebo, read our complete guide:

Complete Placebo Guide

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