Hormonal systems profoundly influence post-traumatic stress disorder. Understanding these connections helps explain the varied timing, patterns, and presentations of post-traumatic stress disorder across the lifespan.
Key Hormones in Post-Traumatic Stress Disorder
Cortisol (the stress hormone): Chronically elevated cortisol from ongoing post-traumatic stress disorder damages the hippocampus and dysregulates the entire stress response system.
Serotonin precursors: Hormonal fluctuations affect tryptophan availability and serotonin synthesis.
Estrogen and testosterone: Influence mood regulation directly and through effects on serotonin and dopamine systems.
Thyroid hormones: Thyroid dysregulation can mimic or worsen post-traumatic stress disorder — always worth screening.
Life Transitions and Hormonal Post-Traumatic Stress Disorder
Hormonal transitions (puberty, postpartum, perimenopause, andropause) are high-risk periods for post-traumatic stress disorder onset or worsening.
Addressing Hormonal Contributions to Post-Traumatic Stress Disorder
If hormonal factors contribute to your post-traumatic stress disorder, treatment may include hormonal evaluation, targeted supplements, hormone therapy, or approaches that support hormonal regulation through lifestyle.