Hormonal systems profoundly influence miscarriage. Understanding these connections helps explain the varied timing, patterns, and presentations of miscarriage across the lifespan.
Key Hormones in Miscarriage
Cortisol (the stress hormone): Chronically elevated cortisol from ongoing miscarriage damages the hippocampus and dysregulates the entire stress response system.
Serotonin precursors: Hormonal fluctuations affect tryptophan availability and serotonin synthesis.
Estrogen and testosterone: Influence mood regulation directly and through effects on serotonin and dopamine systems.
Thyroid hormones: Thyroid dysregulation can mimic or worsen miscarriage — always worth screening.
Life Transitions and Hormonal Miscarriage
Hormonal transitions (puberty, postpartum, perimenopause, andropause) are high-risk periods for miscarriage onset or worsening.
Addressing Hormonal Contributions to Miscarriage
If hormonal factors contribute to your miscarriage, treatment may include hormonal evaluation, targeted supplements, hormone therapy, or approaches that support hormonal regulation through lifestyle.