Hormonal systems profoundly influence dsm. Understanding these connections helps explain the varied timing, patterns, and presentations of dsm across the lifespan.
Key Hormones in DSM
Cortisol (the stress hormone): Chronically elevated cortisol from ongoing dsm damages the hippocampus and dysregulates the entire stress response system.
Serotonin precursors: Hormonal fluctuations affect tryptophan availability and serotonin synthesis.
Estrogen and testosterone: Influence mood regulation directly and through effects on serotonin and dopamine systems.
Thyroid hormones: Thyroid dysregulation can mimic or worsen dsm — always worth screening.
Life Transitions and Hormonal DSM
Hormonal transitions (puberty, postpartum, perimenopause, andropause) are high-risk periods for dsm onset or worsening.
Addressing Hormonal Contributions to DSM
If hormonal factors contribute to your dsm, treatment may include hormonal evaluation, targeted supplements, hormone therapy, or approaches that support hormonal regulation through lifestyle.